NACC ADRC Portal
The ADRC Portal, housed within the NACC Data Platform, is a powerful, secure interface designed to support Alzheimer’s Disease Research Centers (ADRCs) in managing their participant data. The portal provides seamless tools for ADRCs to submit, view, audit, access, and manage multimodal data, ensuring efficiency and transparency in research operations.
For CLARiTI, the ADRC Portal serves as the submission interface for all CLARiTI data types – case report forms, images, fluid bio samples, and digital neuropathology. ADRC users can leverage real-time CLARiTI dashboards, accessible through the "View, Audit, Access Participant Data" section of the portal.
The ADRC Portal, in collaboration with CLARiTI and NACC, continues to evolve, enhancing data accessibility and research capabilities for the ADRC network.
Access to the ADRC portal is granted via your role and permissions assigned within the NACC Directory. Contact your ADRC Administrator and/or claritidata@uw.edu to ensure your NACC Directory contact information is set up correctly.
For more information about the ADRC portals and current status, please visit: NACC Data Platform | National Alzheimer's Coordinating Center
Upcoming Program- and Site-level Dashboards (In Development):
- CLARiTI Payment Dashboard: A dedicated tool to track the status of procedure payments related to CLARiTI participation. Displays completed procedures eligible for payment and their respective payment status.
- CLARiTI Multimodal Data Dashboard: Provides a comprehensive overview of available CLARiTI data, ensuring researchers have a clear view of integrated datasets for analysis.
CLARiTI Connect - Study Update Newsletters
- CLARiTI Connect – April CLARiTI Connect: Dr. Johnson testifies at U.S. Senate, study enrollment updates, subawards issued and more
- CLARiTI Connect - February 19, 2025: Unlocking Dementia Interview w/ Drs. Johnson Kolb & Zetterberg, Study Handbook V2
- CLARiTI Connect - January 22, 2025: Study EDC launched, Flutemetamol tracer to be added and updates from Access Core
- CLARiTI Connect - December 10, 2024: mPI David Wolk on LATE, Study Updates & Meet NACC Data Team
- CLARiTI Connect - October 29, 2024: CLARiTI in the News, Study Start Up Updates, the Importance of Community Research Liaisons and more.
- CLARiTI Connect - September 26, 2024: First CLARiTI Participant, Study Start Up, Interview w/ Dr. Gil Rabinovici
- CLARiTI Connect - August 7, 2024: CLARiTI MRI Sequences, Study Start-Up, Subawards, & New Staff
- CLARiTI Connect – June 5, 2024: P30 Guidance, 6/20 Blood Biomarkers Webinar, and Access Core Updates
- CLARiTI Connect –April 23, 2024: Scope of Work, Updated Study Protocol and Documents & Call for Community Science Partnership Board
- CLARiTI Study Updates - March 25, 2024
- CLARiTI Study Updates - March 4, 2024
- CLARiTI Study Updates - February 2024
Webinars
Upcoming Webinars
TDP43 Summit:
June 12, 2025 - Virtual Attendance: RSVP required
Join us for the 2025 Summit Advancing TDP43 Biomarkers: From Discovery to Application, hosted by the University of Wisconsin-Madison and presented by Alamar Biosciences, Enigma Biomedical Group, and our very own CLARiTI.
We invite scientists interested in TDP-43 biomarker research to join us for this dynamic summit - a collaborative forum to share discoveries and lessons learned and to identify gaps and opportunities in this challenging field. We hope the summit fosters collaboration as we together shape the future of neurodegenerative disease research.
Please RSVP to register for the event and to take advantage of this unique opportunity to engage with leaders in the field. Virtual registration will close on June10, 2025. As a virtual attendee, you'll have access to live-streamed sessions and opportunities for Q&A with top researchers in the field. The Summit will be hosted by Drs. Henrik Zetterberg, Hartmuth Kolb, and Sterling Johnson.
Please feel free to invite colleagues. Visit our website here for more information about the Summit, our speakers, and to view the agenda.
CLARiTI Investigators’ Meeting
May 5-6, 8:30 - 11:30 am PT - San Francisco, CA (At the ADRC Spring Meeting)
Breakfast provided. Updates from each Core Q&A Discussion/Networking 150 max capacity in person. We encourage Site PIs to attend in person. Keep an eye out for your invitation. Option for virtual attendance.
Toolkits and Resources
- CLARiTI Study Documents for ADRC Sites Box Folder (Public)
- CLARiTI Study Start-Up Dashboard
- CLARiTI Handbook
- CLARiTI readiness checklist
- IRB Approved Documents: CLARiTI consent templates, protocol, Return of Results materials and recruitment materials
- Subaward Documents: CLARiTI Scope of Work
- CLARiTI Operations Memo: CLARiTI MRI Protocol
- CLARiTI Design Toolkit for Style, Graphics, Templates
- Documents are only accessible to CLARiTI study personnel. If
you cannot access the links provided, please contact clariti@medicine.wisc.edu and provide
your name, email address, center affiliation and role.
Kelsey Shuda
klshuda@medicine.wisc.edu
(608) 265-0548
- Arizona ADRC
- Boston University ADRC
- Columbia University ADRC
- Duke/UNC ADRC
- Johns Hopkins ADRC
- University of Michigan ADRC
- Northwestern ADRC
- Oregon Health and Science University, ADRC
- Stanford ADRC
- UAB Exploratory ADRC
- UC Davis ADRC
- UCSF ADRC
- University of Kentucky ADRC
- South Texas ADRC
- University of Washington ADRC
- Vanderbilt Exploratory ADRC
- Wisconsin ADRC
- Yale University ADRC
Hanzhe Gao
hgao@medicine.wisc.edu
(608) 262-4585
- 1Florida ADRC
- Cleveland ADRC
- Emory University, Goizueta ADRC
- Indiana University ADRC
- Massachusetts ADRC
- Mayo Clinic ADRC
- Mount Sinai School of Medicine ADRC
- New Mexico Exploratory ADRC
- NYU ADRC
- Penn ADRC / Penn Memory Center
- University of Pittsburgh ADRC
- Rush University Alzheimer's Disease Center
- UC Irvine, ADRC
- UCSD Shiley-Marcos ADRC
- University of Kansas ADRC
- USC ADRC
- Wake Forest University, ADRC
- Washington University Knight AD
CONTACT US / CLARITI CONCIERGE
- To get in touch with CLARiTI Regulatory team, please contact us at: clariti-regulatory@medicine.wisc.edu
- To get in touch with NACC, please contact us at: NACCmail@uw.edu
- To get in touch regarding subawards with NACC, please contact us at: naccgrants@uw.edu
- To get in touch with the Access team, please contact us at: clariti-access@medicine.wisc.edu
- To get in touch with the Return of Results team, please contact Haley Kohl at: hakohl@med.umich.edu
- To get in touch with CLARiTI Neuropathology Core, please contact Erica J. Melief: emelief@uw.edu or email CLARiTI Neuropathology at clariti-neuropathology@uw.edu
- To get in touch with CLARiTI PET Core regarding visual reads, please email mac-clariti-petcore@ucsf.edu
- To get in touch with the CLARiTI Data Management team at NACC regarding data entry, reports, dashboards, please email CLARiTIdata@uw.edu
- To get in touch with questions about sample collection and kits, please contact CLARiTI NCRAD Clinical Research Coordinator Mica Gosnell, gosnellm@iu.edu or call (317) 274-7423.
- Connect with CLARiTI groups on the ADRC Program Community Forum
Partners
National Alzheimer’s Coordinating Center (NACC)
The National Alzheimer’s Coordinating Center (NACC) is home to one of the largest, oldest, and most powerful Alzheimer’s datasets, built in collaboration with more than 42 (37 current) Alzheimer’s Disease Research Centers (ADRCs) throughout the US over the past 20+ years.
NACC will serve as the data coordination center for the project which is in keeping with NACC’s overall priority to facilitate data collection, integration, and sharing of data that advances ADRD research. All NACC data is freely available to researchers. On NACC, there is currently UDS data available on over 40K unique individuals and postmortem data available for over 6K Clinical Core participants. NACC has active collaborations with NCRAD and SCAN/LONI to bridge the extensive data on NACC with datatypes stored separately (biosamples at NCRAD, imaging data at LONI).
National Centralized Repository for AD (NCRAD)
The National Centralized Repository for AD (Foroud; Indiana University) has been supporting genetics and biofluid collection in the center's program since 1990 and is a major source for biofluids nationally pertaining to ADRD. NCRAD. NCRAD has a strong relationship with each center. The blood samples collected for CLARiTI will be done with kits supplied by NCRAD, shipped to NCRAD and assayed at NCRAD. The results will be integrated into the ADRC system at NACC and also given back to the sites.
Standardized Centralized Alzheimer’s & Related Dementias Neuroimaging (SCAN)
SCAN is a U24 collaboration led by Dr. Bill Jagust (UC Berkeley) and Dr. Clifford Jack (Mayo Clinic), colleagues at UC Davis, University of Michigan, and the Laboratory for Neuroimaging (LONI) at University of Southern California to collect standardized MRI and PET data across the ADRC program. The standardized MRI and PET images obtained in CLARITi will reside at LONI. SCAN investigators will QC the PET and MRI data and conduct essential processing to make the data available to the scientific community via NACC. CLARiTI will work with raw and processed standardized images at LONI to achieve its aims including visual reads and any additional quantification in collaboration with relevant entities and investigators.
The National Institute on Aging (NIA) funds 33 Alzheimer’s Disease Research Centers (ADRCs) at major medical institutions across the United States. Researchers at these Centers are working to translate research advances into improved diagnosis and care for people with Alzheimer’s disease, as well as working to find a treatment or way to prevent Alzheimer’s and other types of dementia. In addition, NIA funds 4 Exploratory ADRCs that are designed to expand and diversify research and education opportunities to new areas of the country, new populations, and new areas of science and approaches to research.
CLARiTI will leverage the resources of the NIA-funded P30 Alzheimer’s Research Centers program, which was originally established with 6 funded centers in 1984.